KSR Pain Evidence provides a user-friendly, time-efficient way to access best available evidence in pain management. We summarise systematic reviews and meta-analyses published on the topic of pain since 2010 and provide a short, accessible “bottom line”. Our “bottom line” gives the key clinically relevant implications of the results reported in the article and includes information about the reliability of these results. The database also includes all randomised controlled trials on the topic of pain since 2010.